All,
We at Hobu have been working to use Entwine https://entwine.io to output 3DTiles point clouds for very large collections. You can see a prototype in action at http://cesium.entwine.io
For example, the post-Sandy collection of NYC, which is about 4.7 billion points in size, can be seen at http://cesium.entwine.io/?resource=nyc
We hope you find this interesting, and we look forward to iterating the point cloud aspect of the 3DTiles specification with knowledge and experience we've learned with other renders such as http://speck.ly and http://potree.entwine.io
Help us continue to improve by contributing and participating on the 3DTiles point cloud ticket at https://github.com/AnalyticalGraphicsInc/3d-tiles/issues/22#issuecomment-248426364
Howard