[cesium-dev] Can't get OpenTopoMap tiles to work, any ideas?

It looks like that site does not have CORS headers enabled to allow use of their tiles from other origins. You could try contacting them and asking them to add the proper response headers.

https://developer.mozilla.org/en-US/docs/Web/HTTP/Access_control_CORS

It works with leaflet, and not with cesium. So probably not related to CORS ?