@ChrisDisguise if you would like Cesium to manage the hosting and streaming of your imagery, Cesium ion is the tool for the job. If you need to process data offline and host it yourself (or include it in a local installation), Cesium also offers offline tilers, which you can learn about here:
When using those, you will need to host the data yourself.
Cesium’s formats are all open standards, so there are also third-party options of various levels of quality. I can’t provide support for those, though.
Kevin